Some of the busiest airports in Europe such as London Heathrow Airport (LHR) feature on this list of the busiest international airline routes by region. Although one might expect powerhouses such as Chhatrapati Shivaji Maharaj International Airport (BOM) or Indira Gandhi International Airport (DEL) which make it to the list of the ten busiest domestic flight routes don’t quite make the cut. Let’s take a look at the busiest one international airline routes per region calculated by OAG.
Busiest Flight Route in Africa and Middle East: Cairo – Jeddah
Photo: MarcelX42 | Wikimedia Commons
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| Route | Cairo International Airport (CAI) – King Abdulaziz International Airport (JED) |
| Seats Offered | 5,469,274 seats |
Photo: Fabrizio Berni | Wikimedia Commons
| Distance | 755 miles |
| Approximate Flight Time | 2 hours 10 minutes |
Photo: FlyNas | Wikimedia Commons
A few other airlines operating non-stop flights on the CAI-JED route include:
| Airline | Aircraft | Approximate flight time |
| EgyptAir (MS) | Airbus A330-300 and Boeing 737-800 | 2 hours 10 minutes |
| Nile Air (NP) | Airbus A320-100 | 2 hour 15 minutes |
| Air Arabia Egypt (E5) | Airbus A320-100 | 2 hour 10 minutes |
| Flyadeal (F3) | Airbus A320-100/200 | 2 hours 25 minutes |
Photo: Ken Fielding | Wikimedia Commons
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A few airlines offering a one-stop flight connection on the CAI-JED route include:
| Airline | Stopover at | Total distance | Total flight time |
| Royal Jordanian (RJ) | Queen Alia International Airport (AMM) | 1018 miles | 5h 10m |
| Middle East Airlines (ME) | Beirut–Rafic Hariri International Airport (BEY) | 1223 miles | 7h 00m |
| Saudia (SV) | Prince Mohammad bin Abdulaziz International Airport (MED) | 844 miles | 5h 55m |
| EgyptAir (MS) | Luxor International Airport (LXR) | 815 miles | 7h 40m |
Busiest Flight Route in Asia Pacific: Hong Kong – Taipei
Photo:4300streetcar|Wikimedia Commons
| Routes | Hong Kong -Taipei |
| Seat offered | 6,781,577 seats |
photo: Bill Abbott |Wikimedia Commons
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| Distance | 500 miles |
| Approximate Flight Time | 1hours 45 minutes |
Photo:4300streetcar|Wikimedia Commons
Some other airlines proving non-stop flight services on the Hong Kong – Taipei route are:
| Airline | Aircraft | Approximate Flight Time |
| Eva Air (BR) | Boeing 787-10 | 1hours 45 Minutes |
| Cathay Pacific(CPA) | Boeing 777-300 | 1 hours 55 Minutes |
| Hong Kong Airlines(HX) | Airbus A330-300 | 1 hours 55 Minutes |
Photo: Jubair Bin Iqbal |Wikimedia Commons
Some airlines providing one-stop flight connections on this route are:
| Airlines | Stopover at | Total Distance | Total Flight time |
| Eva Air (BR) | Guangzhou Baiyun International Airport (CAN) | 964 km | 5h 45m |
Besides, Xiamen airlines is also set to provide one stop services on this route [as per data from Flight Routes] from 2025-03-31.
Busiest Flight Route in Europe and North America: New York JFK – London Heathrow
Photo: Lasse Fuss |Wikimedia commons
| Routes | John F. Kennedy International Airport (JFK) – Heathrow Airport (LHR) |
| Seat offered | 4,011,235 |
Photo: New York-air|Wikimedia Commons
| Distance | 3440 miles |
| Approximate Flight Time | 7h 00 |
Photo:4300streetcar|Wikimedia commons
Some of the airlines operators which are providing non-stop services on this route are:
| Airline | Aircraft | Approximate Flight Time |
| American Airlines (AA) | Boeing 777-200 / 200ER | 6 hours 55 minutes |
| British Airways(BA) | Boeing 777 | 7 hours |
| Virgin Atlantic(VS) | Airbus A350-1000 | 7 hour 10 minutes |
Photo: John Robert McPherson |Wikimedia Commons
Some of the other airlines providing one-stop flight connections on this route are:
| Airlines | Stopover at | Total Distance | Total Flight time |
| Icelandair (FL) |
Reykjavik Keflavik International Airport (KEF) | 6090 km | 10 hours 25 minutes |
| American Airlines (AA) | Boston Logan International Airport (BOS) | 5569 km | 9 hours 10 minutes |
|
Scandinavian Airlines (SK)
|
Copenhagen Kastrup Airport (CPH) | 7205 km | 10 hours 35 minutes |
Busiest Flight Route in Latin America: Orlando – San Juan
Photo: Laurent ERRERA|Wikimedia commons
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| Route | Orlando International Airport (MCO) – Luis Muñoz Marín International Airport (SJU) |
| Seats offered | 2,309,653 |
Photo: Martin Falbisoner|Wikimedia Commons
| Distance | 1,188 miles |
| Approximate Flight Time | 2 hour 55 minutes |
Photo: Eddie Maloney |Wikimedia commons
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Some of the airlines providing non-stop flights on this busiest route in Latin America are:
| Airline | Aircraft | Approximate Flight Time |
| Spirit Airlines (NK) | Airbus A320 (sharklets) | 2 hour 47 minutes |
| Southwest Airlines (WN) | Boeing 737 | 2 hour 50 minutes |
| JetBlue Airways (B6) | Airbus A320 | 2 hour 53 minutes |
Photo: Milad A380 |Wikimedia Commons
Some of the airlines providing one stop flight connections on this route are:
| Airlines | Stopover at | Total Distance | Total Flight time |
| Spirit Airlines (NK) | Fort Lauderdale Hollywood International airport (FLL) | 1231 miles | 5 hours 37 minutes |
| American Airlines (AA) | Miami International Airport (MIA) | 1245 miles | 6 hours 22 minutes |